Particle Sciences strengthens nanomilling offering with new API screening program
CLEVELAND, Ohio, Jan 10, 2019 - (ACN Newswire) - The Lubrizol Corporation announces its contract development and manufacturing organization (CDMO), Particle Sciences, a Lubrizol LifeSciences company, has strengthened its nanomilling offering with the launch of a new Nanomilling Feasibility Program.
The program is designed to assess nanomilling as a dissolution/solubility enhancement option for a client's active pharmaceutical ingredient (API). In as little as eight weeks, Particle Sciences will nanomill an API with GRAS-approved excipients, measure particle size distribution and obtain short-term stability data to identify promising formulations. Pre-clinical test samples will then be made available to clients for pharmacokinetic studies.
Up to 90 percent of APIs in the discovery pipeline are poorly water-soluble, resulting in poor bioavailability and challenges for dosage form development. Nanomilling is commercially validated with 12 nanomilled drug products approved by the FDA since 2000 including Aristada(R) and Invega Sustenna(R). Over the years, Particle Sciences has nanomilled scores of APIs, including new chemical entities as well as those found in marketed products.
Dr. Robert Lee, president of Particle Sciences states, "With so many poorly water-soluble drug candidates emerging from drug discovery, advanced formulation techniques like nanomilling are increasingly in demand and may provide an excellent route to improved bioavailability and enhanced therapeutic effect. While several companies now have nanomilling equipment, few have the extensive knowledge on stabilizing nanoparticulate suspensions and the analytical capabilities that we do. We are also the only CDMO that offers cGMP nanomilling under aseptic conditions."
Particle Sciences has decades of experience developing nanoparticulate suspensions, both with commercial milling equipment and its own proprietary mills. The CDMO has the facilities and equipment to produce clinical and commercial-scale nanomilled formulations.
Dr. Lee continues, "Our expertise in this area means we can determine within a short timeframe if nanomilling is a viable technology to improve the solubility of a client's API and facilitate the decision-making process for their project."
Further information on Particle Sciences' Nanomilling Feasibility Program can be found at https://bit.ly/2QBqCWg
Particle Sciences is part of Lubrizol Advanced Materials Inc.
About Particle Sciences
Particle Sciences, a Lubrizol LifeSciences company, is an integrated provider of drug development services. Particle Sciences focuses on BCS II/III/IV molecules, biologics and highly potent compounds through a variety of technologies including emulsions, gels, micro and nano-particulates, drug/device combination products, solid solutions and others. Particle Sciences is FDA registered and DEA licensed. Through a full range of formulation, analytic and manufacturing services, Particle Sciences provides pharmaceutical companies with a complete and seamless development solution that minimizes the time and risk between discovery and the clinic. The company was founded in 1991 and is headquartered in Bethlehem, Pennsylvania.
About Lubrizol LifeSciences
Lubrizol LifeSciences is a preferred Contract Development and Manufacturing Organization (CDMO) partner for complex pharmaceuticals and high-end medical devices providing differentiated polymers and excipients, along with state-of-the-art design, development and manufacturing services to the healthcare industry.
About The Lubrizol Corporation
The Lubrizol Corporation, a Berkshire Hathaway company, is a market-driven global company that combines complex, specialty chemicals to optimize the quality, performance and value of customers' products while reducing their environmental impact. It is a leader at combining market insights with chemistry and application capabilities to deliver valuable solutions to customers in the global transportation, industrial and consumer markets. Lubrizol improves lives by acting as an essential partner in our customers' success, delivering efficiency, reliability or wellness to their end users. Technologies include lubricant additives for engine oils, driveline and other transportation-related fluids, industrial lubricants, as well as additives for gasoline and diesel fuel. In addition, Lubrizol makes ingredients and additives for home care, personal care and skin care products and specialty materials encompassing polymer and coatings technologies, along with polymer-based pharmaceutical and medical device solutions.
With headquarters in Wickliffe, Ohio, Lubrizol owns and operates manufacturing facilities in 17 countries, as well as sales and technical offices around the world. Founded in 1928, Lubrizol has approximately 8,700 employees worldwide. Revenues for 2017 were $6.3 billion. For more information, visit Lubrizol.com.
+44 (0)191 222 1242
This announcement is distributed by West Corporation on behalf of West Corporation clients.
The issuer of this announcement warrants that they are solely responsible for the content, accuracy and originality of the information contained therein.
Source: Lubrizol via Globenewswire
Copyright ©2021 ACN Newswire. All rights reserved. A division of Asia Corporate News Network.
Latest Press Release
More Latest Release >>
New roads await the Toyota Yaris WRC in Croatia
Apr 16, 2021 18:09 JST
Showa Denko Announces Share Transfer with Change in Subsidiary
Apr 16, 2021 16:30 JST
Fujitsu Updates Group Environmental Plan to Achieve Validation of 1.5 degrees Celcius - Aligned Emissions Reduction Targets, Contribute to Sustainable Future
Apr 16, 2021 10:17 JST
Local Production of Hitachi Automatic Analyzer 3500 to Commence in China
Apr 15, 2021 16:42 JST
NextDecade and Mitsubishi Heavy Industries America Execute Engineering Services Agreement for Carbon Capture at Rio Grande LNG Project in Texas
Apr 15, 2021 13:56 JST
Fujitsu Fuels Big Data Innovation in Mobility Space with Launch of "Digital Twin Collector" Platform
Apr 15, 2021 10:44 JST
Mitsubishi Power Receives Order for Two Gas Turbines for 1,500MW Class GTCC Power Plant in Uzbekistan
Apr 14, 2021 15:36 JST
Honda to Introduce First Energy Service for Europe - e:PROGRESS - in the UK
Apr 14, 2021 15:11 JST
Eisai to Present Latest Data on Neurology Products and Pipelines at the American Academy of Neurology Annual Meeting
Apr 14, 2021 13:49 JST
Mazda3 Named Canadian Car of the Year 2021
Apr 14, 2021 12:47 JST
Tokyo Century and DOCOMO to Globally Expand EDGEMATRIX Edge-AI Platform for Video Surveillance & Monitoring
Apr 13, 2021 17:57 JST
Fujitsu Renews Key Systems for Japan Meteorological Agency, Contributing to Completion of Centralized Virtualization Platform
Apr 13, 2021 15:28 JST
NEC recognized as a Partner of the Year by Juniper Networks for two consecutive years
Apr 13, 2021 11:52 JST
Eisai: Animation Featuring Lymphatic Filariasis Elimination Activities Receives Animation Award at International Society for Neglected Tropical Diseases Festival 2021
Apr 12, 2021 13:16 JST
Fujitsu Embarks on Partnership with Siemens Digital Industries Software Strengthening Global Competitiveness and Accelerating DX to Realize Smart, Sustainable Manufacturing
Apr 12, 2021 11:48 JST
Lexus to Display LF-Z Electrified Concept and New ES
Apr 12, 2021 11:09 JST
MHI Invests in Starfire Energy, a Modular Green Ammonia Solution Provider, to Accelerate Efforts to Energy Transition
Apr 09, 2021 17:22 JST
DENSO Develops Advanced Driver Assistance Products for New Lexus LS, Toyota Mirai
Apr 09, 2021 13:46 JST
Deltacore Capital launches Deltacore Digital Global LP
Apr 09, 2021 13:30 JST
Hitachi Astemo to showcase advanced mobility solutions at Auto Shanghai 2021
Apr 09, 2021 13:05 JST