NEC OncoImmunity AS and Oslo University Hospital Team Up to Develop a Diagnostic for COVID-19 using Artificial Intelligence
OSLO, NORWAY, Oct 08, 2020 - (JCN Newswire) - NEC OncoImmunity AS (NOI), a subsidiary of NEC Corporation (NEC), and Oslo University Hospital (OUH) are pleased to announce that they have recently been awarded a prestigious grant from the Research Council of Norway (RCN) to develop an artificial intelligence (AI) platform that will enable the rapid design of T-cell diagnostics for emerging or endemic infectious diseases. The project will develop a novel T-cell diagnostic for the current COVID-19 pandemic to complement the current serological tests. This will improve the ability to identify immune responses and acquired immunity, which is desperately needed to deal with the COVID-19 crisis.
Current technologies involve extensive trial and error to define exactly which parts of the pathogen induce robust immunity. These so called immunodominant epitopes need to be identified for the general population. These demanding, work-intensive and time-consuming steps are necessary to develop tests to monitor the T-cell response to viruses such as SARS-CoV-2 (the infectious virus that causes COVID-19).
Reliable diagnostic tests to identify immune individuals are critical to overcome the ever-looming threat of COVID-19. The AI based diagnostic to be developed in this project will complement antibody tests and enable individuals who are naturally immune to the virus following infection with SARS-CoV-2 or other seasonal coronaviruses, or who have acquired immunity following vaccination, to be identified.
"Antibody tests are an important aspect of understanding the immune response to the SARS-CoV-2 infection and will remain a mainstay of its diagnosis. However, protective SARS-CoV-2-specific T-cell responses occur in antibody-negative infected individuals who have successfully resolved the infection. In addition, we may already have underlying immunity in the population due to cross-reactivity to endemic seasonal human coronaviruses," said, Professor Ludvig A. Munthe Ph.D., Head of Research and Group Leader, Department of Immunology, Oslo University Hospital.
Although the technology to develop antibody diagnostics is readily available, this is not the case for T-cell diagnostics, which currently represents a "blind spot" for the monitoring of immunity to COVID-19 in the world's population. To address this important gap, NOI and OUH, with the support of RCN, have now committed themselves to develop an AI-designed T-cell diagnostic that monitors the underlying T-cell response to the infection. Developing a reliable T-cell diagnostic comes with specific technological challenges with solutions offered by the NEC Immune Profiler at NOI to cater to the global human population.
"T-cells are known to play a central role for initial and long term immunity against viruses. However, T-cell responses are highly variable between different pathogens and genetic groups in the human population, making the prospect of developing a reliable universal T-cell diagnostics for COVID-19 challenging. This challenge has inspired the scientists at NOI to use our AI to seek out the T-cell response to infection as a diagnostic signal. In this project we look forward to adapting the NEC Immune Profiler and other AI technologies at NEC Corporation and leveraging them to develop a COVID-19 T-cell diagnostic for the diverse genetic makeup in the global human population," said Trevor Clancy Ph.D., Chief Scientific Officer, NEC OncoImmunity AS.
The development of such an AI platform will not only help to contact-trace and control transmission against COVID-19. In fact, the platform developed by NOI and NEC in this project will be to a large degree pathogen/disease agnostic and may be used in future emergency settings to rapidly develop novel diagnostics against new emerging pandemics caused by novel dangerous infectious agents.
"The AI platform will be applied first to the current COVID-19 pandemic. However, we will design this platform to be future-proof and make it applicable to any future emerging infectious agent that could threaten the global population. This will open up new exciting opportunities in the growing infectious disease diagnostics market for our company," said Richard Stratford Ph.D., Chief Executive Officer, NEC OncoImmunity AS.
It has been over a century since the world has encountered a pandemic like COVID-19. The pandemic has taken over one million lives to date, and the spread of COVID-19 around the globe and the associated mortality has been devastating. The pandemic has sparked fears of a chronic worldwide recession. Shut-downs, social distancing, and travel restrictions have reduced the capacity of the global workforce and destroyed many jobs and businesses. The NOI and OUH collaboration mark an important initiative to develop a reliable diagnostic test that can identify immune members of the global population following natural infection with SARS-CoV-2 or other seasonal coronaviruses.
"A reliable T-cell diagnostic to help alleviate the socio-economic and serious health burden caused by COVID-19 will be important for the world community to overcome this present pandemic crisis. We are proud that NEC's AI technology can contribute to the resolution of the COVID-19 threat. As a company that seeks to enhance the well-being of society, NEC will continue to capitalize on research and development that maximizes the strengths of our AI technology to help prevent the spread of COVID-19, and protect the human population against future pandemic threats," said Akira Kitamura, General Manager of the AI Drug Development Division, NEC Corporation.
About NEC OncoImmunity AS
NEC OncoImmunity AS is a bioinformatics company offering proprietary machine learning-based software called the NEC Immune Profiler, which addresses the key knowledge gaps in the prediction of bona fide immunogenic neoantigens for personalized cancer immunotherapy. The NEC Immune Profiler can be used to identify optimal neoantigen targets for truly personalized cancer vaccines & cell therapies in a clinically actionable timeframe, and also facilitate effective patient selection for cancer immunotherapy. For more information, visit NEC OncoImmunity AS at http://www.oncoimmunity.com/.
About NEC Corporation
NEC Corporation has established itself as a leader in the integration of IT and network technologies while promoting the brand statement of "Orchestrating a brighter world." NEC enables businesses and communities to adapt to rapid changes taking place in both society and the market as it provides for the social values of safety, security, fairness and efficiency to promote a more sustainable world where everyone has the chance to reach their full potential. For more information, visit NEC at https://www.nec.com.
For additional information, please also visit NEC Laboratories Europe GmbH at: https://www.neclab.eu
About Oslo University Hospital
Oslo University Hospital is a part of Southern and Eastern Norway Regional Health Authority and an OECI-accredited Comprehensive Cancer Center (CCC). Each year, more than 1.2 million patient treatments are carried out at the hospital, which is the largest of its kind in Scandinavia. Oslo University Hospital is owned by the South-Eastern Norway Regional Health Authority (HSO) and delivers specialist healthcare services to patients all over Norway. Oslo University Hospital is Norway's largest hospital with around 20,000 employees and is responsible for a significant proportion of the medical research and the education of medical personnel in the country. More information about Oslo University Hospital can be found at new windowhttps://oslo-universitetssykehus.no.
Source: NEC Corporation Sectors: BioTech, Artificial Intel [AI]
Copyright ©2024 JCN Newswire. All rights reserved. A division of Japan Corporate News Network.
|
Latest Release
Mitsubishi Shipbuilding Receives Order from the University of Tokyo for "MiPoLin" Power Prediction and Lines Selection System Mar 28, 2024 16:45 JST
| Mitsubishi Logisnext Completes Demonstration of Automated Truck Loading, Leading to Start of Actual Operations in Japan Mar 28, 2024 13:52 JST
| Toyota Releases Sales, Production, and Export Results for February 2024 Mar 28, 2024 13:35 JST
| TANAKA to Install 500 kW Fuel Cell System to Promote the Use of Hydrogen Energy at Production Plants Mar 28, 2024 03:00 JST
| PEVE to change name to TOYOTA BATTERY Co., Ltd. and produce batteries for a wide range of electric vehicles Mar 27, 2024 15:13 JST
| NTT and Olympus Begin World's First Joint Demonstration Experiment of Cloud Endoscopy System Mar 27, 2024 15:00 JST
| TANAKA Holdings Announces Green Loan Financing for Construction of New Head Office Building Mar 27, 2024 03:00 JST
| JFE Steel and Hitachi Jointly Started Providing Solutions for the Steel Industry Mar 26, 2024 19:04 JST
| La Banque Postale and JCB join forces to elevate payments experience for travellers in France Mar 26, 2024 15:00 JST
| Fujitsu Tech Leverages AI and Underwater Drone Data for 'Ocean Digital Twin' Mar 26, 2024 10:24 JST
| NEC develops marketing strategy planning & effectiveness simulation technology using generative AI Mar 25, 2024 10:08 JST
| Toyota to Open New Tokyo Head Office in Shinagawa in FY2030 Mar 22, 2024 16:15 JST
| Hitachi Selected as CDP Supplier Engagement Leader for the Third Consecutive Year Mar 22, 2024 16:04 JST
| Mitsubishi Motors Celebrates Production of 100,000th fully electric minivehicle Mar 22, 2024 15:34 JST
| JCB and AEON Credit Service Indonesia Launch the AEON JCB Precious Card Mar 22, 2024 15:00 JST
| JCB Issues White Paper on Calculating CO2 Emissions by Payment Method in Japan Mar 22, 2024 12:00 JST
| NEC and NTT successfully conduct first-of-its-kind long-distance transmission experiment over 7,000km using 12-core optical fiber Mar 22, 2024 08:38 JST
| Lifenet and Eisai Co-Develop Dementia Insurance "be" Mar 21, 2024 17:36 JST
| Toyota: Clarification of the Roles of and Expectations for Outside Executives, Revision of the Independence Assessment Criteria, and the Changes to Members of the Board of Directors and the Audit and Supervisory Board Members following the 120th Ordinary General Shareholders' Meeting Mar 21, 2024 16:47 JST
| Sales of Evolved GR Yaris to Start in April, While Purchasing Lotteries for WRC Driver-supervised Special Editions Start Today Mar 21, 2024 16:31 JST
|
More Latest Release >>
|